We are seeking a staff scientist to join the Fabbri Lab. Research projects will focus on the role of microRNAs and other non-coding RNAs in the tumor microenvironment (TME). We study how non-coding RNAs in extracellular vesicles affect cancer biology and how this knowledge can lead to to develop new anti-cancer therapies through CRISPR-drug screening. Candidates are expected to be familiar with the following techniques: cell culture, transfections, cloning, DNA and RNA isolation, immunoblotting, PCR, real-time PCR, MTT assays, cytofluorimetry, CRISPR gene editing. In vivo experience with cancer mouse models (xenografts or orthotopic models) is required. Knowledge of statistics for data analysis and interpretation is desirable. Candidates should be able to design and execute laboratory experiments, interpret experimental results, work well in a team environment, contribute to weekly lab meetings, and present data in a clear and concise manner.

The Staff Scientist III position is a senior role requiring a PhD degree and reporting to a principal investigator or CNRI center director. This position requires a high level of professionalism and expertise and will serve in several roles in the research center depending on the scientific specialty and the needs of the laboratory. The Staff Scientist III creates opportunities to enhance technical methodology or content through the expansion of existing or development of new efforts, and may extend technology into new application areas. The Staff Scientist III supervises junior scientists, graduate students and technicians and works independently or with technical guidance from the principal investigator.

• Consistently demonstrates adherence to the standards for the responsible conduct of research.

• Plans, conducts and manages research projects within federal and institutional regulations and policies under the direction of the principal investigator.

• Uses research funds and resources appropriately.

• Maintains confidentiality of data as required.

• Meets all annual job-related training and compliance requirements.

• Conducts research of significant scientific value in the basic and/or translational science areas relevant to practice specialty.

• Participates in reviewing manuscripts for peer-reviewed journals.

• Publishes in peer-reviewed, scientific, quality and management journals.

• Submits applications for grants or contracts for funding of research projects.

• Collects, codes and compiles statistics (coding of data requires interpretation of data from a broad range of alternatives).

• Contributes to or leads in major intellectual development activities.

• Mentors graduate/post-doctoral students.

• Participates in educational programs, teaching assignments, technical meetings, workshops and committees.

• Creates opportunities to enhance technical methodology or content through the expansion of existing or development of new efforts.

• Assists with the management of resource allocations and manages day-to-day activities in the laboratory, such as purchasing, oversight of laboratory animals, radioactivity and biosafety issues.

• Applies innovative problem-solving approaches to enhance organizational capabilities and uses peer network to expand technical capabilities and identify new research opportunities in collaboration with the principal investigator.

• Generates standard and ad-hoc reports as needed.

• Analyzes and evaluates data.

• Develops and modifies databases as needed.

• Compiles data and writes sections of project results and analysis.

• Edits sections written by colleagues.

• Prepares charts and graphs for publication.

• Drafts and edits manuscripts and grant proposals.

• Partner in the mission and upholds the core principles of the organization

• Committed to diversity and recognizes value of cultural ethnic differences

• Demonstrate personal and professional integrity

• Maintain confidentiality at all times

• Anticipate and responds to customer needs; follows up until needs are met

• Demonstrate collaborative and respectful behavior

• Partner with all team members to achieve goals

• Receptive to others' ideas and opinions

• Contribute to a positive work environment

• Demonstrate flexibility and willingness to change

• Identify opportunities to improve clinical and administrative processes

• Make appropriate decisions, using sound judgment

• Use resources efficiently

• Search for less costly ways of doing things

• Speak up when team members appear to exhibit unsafe behavior or performance

• Continuously validate and verify information needed for decision making or documentation

• Stop in the face of uncertainty and takes time to resolve the situation

• Demonstrate accurate, clear and timely verbal and written communication

• Actively promote safety for patients, families, visitors and co-workers

• Attend carefully to important details - practicing Stop, Think, Act and Review in order to self-check behavior and performance